Recent Publications

(in inverse chronological order, since 2016-present, as corresponding author *)


  1. Liu Dong#, Liu Yingying#, Duan Hua-Zhen, Chen Xinjie, Wang Yanan, Wang Ting, Yu Qing, Chen Yong-Xiang*, & Lu Yuan#. (2023). Customized synthesis of phosphoprotein bearing phosphoserine or its nonhydrolyzable analog. Synthetic and Systems Biotechnology, 8(1), 69-78. https://doi.org/10.1016/j.synbio.2022.11.004
  1. Duan Hua-Zhen#, Hu Cheng#, Li Yue-Lin, Wang Shi-Hao, Xia Yan, Liu Xiaohong*, Wang Jiangyun*, & Chen Yong-Xiang*. (2022). Genetically Encoded Phosphine Ligand for Metalloprotein Design. Journal of the American Chemical Society, 14(50), 22831-22837. https://doi.org/10.1021/jacs.2c09683
  1. Chang Rong, Chen Jia-Lin, Zhang Guan-Yi, Li Yue, Duan Hua-Zhen, Luo Shi-Zhong*, & Chen Yong-Xiang*. (2022). Intrinsically Disordered Protein Condensate-Modified Surface for Mitigation of Biofouling and Foreign Body Response. Journal of the American Chemical Society, 144(27), 12147-12157. https://doi.org/10.1021/jacs.2c02677
  1. Chang Rong#, Liu Yang-Jia#, Zhang Yun-Lai, Zhang Shi-Ying, Han Bei-Bei, Chen Feng*, & Chen Yong-Xiang*. (2022). Phosphorylated and Phosphonated Low-Complexity Protein Segments for Biomimetic Mineralization and Repair of Tooth Enamel. Advanced Science, 2103829, Article 2103829. https://doi.org/10.1002/advs.202103829
  1. Wu Jun-Jun#, Chen Fang-Yuan#, Han Bei-Bei#, Zhang Hong-Qing#, Zhao Lang, Zhang Zhe-Rui, Li Juan-Juan, Zhang Bo-Dou, Zhang Ya-Nan, Yue Yu-Xin, Hu Hong-Guo, Li Wen-Hao, Zhang Bo*, Chen Yong-Xiang*, Guo Dong-Sheng*, & Li Yan-Mei*. (2022). CASTING: A Potent Supramolecular Strategy to Cytosolically Deliver STING Agonist for Cancer Immunotherapy and SARS-CoV-2 Vaccination. CCS Chemistry. https://doi.org/10.31635/ccschem.022.202201859
  1. Li Yue, Chang Rong, & Chen Yong-Xiang*. (2022). Recent Advances in Post-polymerization Modifications on Polypeptides: Synthesis and Applications. Chemistry-an Asian Journal, 17, e20220031, Article e202200318. https://doi.org/10.1002/asia.202200318
  1. Hu Jun, Sun Xue-Meng, Su Jing-Yun, Zhao Yu-Fen, & Chen Yong-Xiang*. (2021). Different phosphorylation and farnesylation patterns tune Rnd3-14-3-3 interaction in distinct mechanisms. Chemical Science, 12(12), 4432-4442. https://doi.org/10.1039/d0sc05838f
  1. Zhu Peng-Cheng, & Chen Yong-Xiang*. (2021). Facile Synthesis of Boc-Protected Selenocystine and its Compatibility with Late-Stage Farnesylation at Cysteine Site. Protein and Peptide Letters, 28(6), 603-611. https://doi.org/10.2174/0929866527666201223094249
  1. Li Fang-Yi, Zhang Zhen-Feng, Voss Stephanie, Wu Yao-Wen, Zhao Yu-Fen, Li Yan-Mei, & Chen Yong-Xiang*. (2020). Inhibition of K-Ras4B-plasma membrane association with a membrane microdomain-targeting peptide. Chemical Science, 11(3), 826-832. https://doi.org/10.1039/c9sc04726c

  1. Duan Hua-Zhen, Nie Zhen-Ke, Li Yue, & Chen Yong-Xiang*. (2020). Unremitting progresses for phosphoprotein synthesis. Current Opinion in Chemical Biology, 58, 96-111. https://doi.org/10.1016/j.cbpa.2020.07.009

  2. Hackenberger Christian P. R.*, Dawson Philip E.*, Chen Yong-Xiang*, & Hojo Hironobu*. (2020). Modern Peptide and Protein Chemistry: Reaching New Heights [Editorial Material]. Journal of Organic Chemistry, 85(3), 1328-1330. https://doi.org/10.1021/acs.joc.0c00104

  3. Han Bei-Bei#, Pan Yu-Chen#, Li Yan-Mei, Guo Dong-Sheng*, & Chen Yong-Xiang*. (2020). A host-guest ATP responsive strategy for intracellular delivery of phosphopeptides. Chemical Communications, 56(41), 5512-5515. https://doi.org/10.1039/d0cc01800g

  1. Zhang Yun-Lai, Chang Rong, Duan Hua-Zhen, & Chen Yong-Xiang*. (2020). Metal ion and light sequentially induced sol-gel-sol transition of a responsive peptide-hydrogel. Soft Matter, 16(33), 7652-7658. https://doi.org/10.1039/d0sm00442a
  1. Duan Hua-Zhen, Chen Hong-Xue, Yu Qing, Hu Jun, Li Yan-Mei, & Chen Yong-Xiang*. (2019). Stereoselective synthesis of a phosphonate pThr mimetic via palladium-catalyzed gamma-C(sp(3))-H activation for peptide preparation. Organic & Biomolecular Chemistry, 17(8), 2099-2102. https://doi.org/10.1039/c8ob02999g
  1. Gao Na, Huang Yun-Peng, Chu Ting-Ting, Li Qian-Qian, Zhou Bing, Chen Yong-Xiang*, Zhao Yu-Fen, & Li Yan-Mei*. (2019). TDP-43 specific reduction induced by Di-hydrophobic tags conjugated peptides. Bioorganic Chemistry, 84, 254-259. https://doi.org/10.1016/j.bioorg.2018.11.042
  1. Chen Hong-Xue#, Kang Jie#, Chang Rong, Zhang Yun-Lai, Duan Hua-Zhen, Li Yan-Mei, & Chen Yong-Xiang*. (2018). Synthesis of alpha,alpha-Difluorinated Phosphonate pSer/pThr Mimetics via Rhodium-Catalyzed Asymmetric Hydrogenation of beta-Difluorophosphonomethyl alpha-(Acylamino)acrylates. Organic Letters, 20(11), 3278-3281. https://doi.org/10.1021/acs.orglett.8b01151
  1. Huang Si-Qi, Han Bei-Bei, Li Yan-Mei, & Chen Yong-Xiang*. (2018). A site-specific branching poly-glutamate tag mediates intracellular protein delivery by cationic lipids. Biochemical and Biophysical Research Communications, 503(2), 671-676. https://doi.org/10.1016/j.bbrc.2018.06.059
  1. Hu Jun#, Zhu Pengcheng#, Li Yanmei, & Chen Yong-Xiang*. (2018). Synthesis of Ras proteins and their application in biofunctional studies. Chinese Chemical Letters, 29(7), 1043-1050. https://doi.org/10.1016/j.cclet.2018.05.035
  1. Yu Qiuhong, Sun Jianbo, Huang Siqi, Chang Haojing, Bai Qingwen, Chen Yong-Xiang*, & Liang Dehai*. (2018). Inward Budding and Endocytosis of Membranes Regulated by de Novo Designed Peptides. Langmuir, 34(21), 6183-6193. https://doi.org/10.1021/acs.langmuir.8b00882
  1. Zhang Si-Yu, Sperlich Benjamin, Li Fang-Yi, Al-Ayoubi Samy, Chen Hong-Xue, Zhao Yu-Fen, Li Yan-Mei, Weise Katrin, Winter Roland*, & Chen Yong-Xiang*. (2017). Phosphorylation Weakens but Does Not Inhibit Membrane Binding and Clustering of K-Ras4B. Acs Chemical Biology, 12(6), 1703-1710. https://doi.org/10.1021/acschembio.7b00165
  1. Kang Jie#, Chen Hong-Xue#, Huang Si-Qi, Zhang Yun-Lai, Li Fang-Yi, Li Yan-Mei, & Chen Yong-Xiang*. (2017). Facile synthesis of Fmoc-protected phosphonate pSer mimetic and its application in assembling a substrate peptide of 14-3-3 zeta. Tetrahedron Letters, 58(26), 2551-2553. https://doi.org/10.1016/j.tetlet.2017.05.037
  1. Gao Na, Chu Ting-Ting., Li Qian-Qian, Lim Yeh-Jun, Qiu Tian, Ma Meng-Rong, Hu Zhi-Wen, Yang Xi-Fei, Chen Yong-Xiang*, Zhao Yu-Fen, & Li Yan-Mei*. (2017). Hydrophobic tagging-mediated degradation of Alzheimer’s disease related Tau. Rsc Advances, 7(64), 40362-40366. https://doi.org/10.1039/c7ra05347a
  1. Shi Lei, Chen Huai, Zhang Si-Yu, Chu Ting-Ting, Zhao Yu-Fen, Chen Yong-Xiang*, & Li Yan-Mei*. (2017). Semi-synthesis of murine prion protein by native chemical ligation and chemical activation for preparation of polypeptide–thioester. Journal of Peptide Science, 23(6), 438-444. https://doi.org/10.1002/psc.3008
  1. Chu Ting-Ting, Gao Na, Li Qian-Qian, Chen Pu-Guang, Yang Xi-Fei, Chen Yong-Xiang*, Zhao Yu-Fen, & Li Yan-Mei. (2016). Specific Knockdown of Endogenous Tau Protein by Peptide-Directed Ubiquitin-Proteasome Degradation. Cell Chemical Biology, 23(4), 453-461. https://doi.org/10.1016/j.chembiol.2016.02.016
  1. Li Lei, Zhang Si-Yu, Li Yan-Mei, & Chen Yong-Xiang*. (2016). Dual-labeling of ubiquitin proteins by chemoselective reactions for sensing UCH-L3. Molecular Biosystems, 12(6), 1764-1767. https://doi.org/10.1039/c6mb00165c
  1. He Yao-Hui, Li Yan-Mei, & Chen Yong-Xiang*. (2016). Phosphorylation regulates proteolytic efficiency of TEV protease detected by a 5(6)-carboxyfluorescein-pyrene based fluorescent sensor. Talanta, 150, 340-345. https://doi.org/10.1016/j.talanta.2015.12.028